Authenticity

6,077,872

Use of calcium L-threonate in preventing, inhibiting and curing osteoporosis and rickets.
Abstract: The present invention relates to the use of calcium L-threonate, namely, to a method for preventing, inhibiting and curing osteoporosis and rickets using calcium L-threonate.

6,713,513 B2

Method for treating cartilage related diseases.
Abstract: The present invention relates to a method for preventing or treating of cartilage related diseases, such as osteoarthritis, rheumatoid arthritis, articular cartilage damage, multiple chondritis, osteochondrosis, etc., which comprises administering an effective amount of calcium L-threonate to a subject in need of such prevention or treatment. It had been demonstrated by experiments that calcium L-threonate could improve significantly the positive expression percentage of collagen I mRNA in the chondrocyte and osteoblast, improved significantly the positive expression percentage of articular cartilage and epiphyseal cartilage, facilitated the growth of chondrocyte, increased the quantity of bone collagen, and promoted the formation of bone and cartilage matrix and the synthesis of proteoglycan. It could also promote the formation of bone nourishing blood vessels and improve the microcirculation of bone.

6,727,288 B2

Calcium L-Threonate Method for treating bone fracture.
Abstract: The present invention relates to a method for treating or preventing bone fracture, which comprises administering an effective amount of calcium L-threonate to a subject in need of such prevention or treatment. It had been found from experiments that calcium L-threonate could not only promote proliferation, differentiation and mineralization of osteoblasts, but also could promote the expression of collagen I mRNA of osteoblasts cultured in vitro. Accordingly it facilitated bone fracture healing and increased bone density and mechanical performance, so as to prevent or treat bone fracture.